Howe ton, Mass., the son of Samuel Hubbard and Eliz- abeth Hubbard (Moore) Howe. He was de- scended from John Howe of Sudbury who be- came a freeman of Massachusetts Bay Colony in 1640 and died in Marlboro in 1680. While An- drew was still a child his father moved to Leices- ter where the boy received his early education in the district school and under the wise direction of his mother. Though he was intensely fond of outdoor activities, his love for books early be- came paramount. He began the study of medi- cine under Dr. Calvin Newton, attending lec- tures at Worcester Medical Institute. Feeling the lack of preparatory training, he returned to Leicester and entered the academy there. After three years' close application, he entered Har- vard, from which he was graduated in 1853. Under the spell of the brilliant Agassiz, young Howe was attracted to geology as a possible life work, but returned to his original choice, medi- cine. Dr. Frank H. Kelley of Worcester became his preceptor for a time, and in 1853 he entered Jefferson Medical College, Philadelphia. The following year he went to New York, where he attended lectures and walked the wards of the hospitals, steadily advancing in knowledge of clinical medicine and surgery. He then returned to Worcester Medical Institute. Upon his grad- uation in 1855, his attainments were such that he was appointed demonstrator of anatomy, from which position he soon advanced to the profes- sorship of anatomy. For six months he efficient- ly cared for the surgical practice of Dr. Walter Burnham, and then opened an office for himself in Worcester. In 1856 he was invited to lecture in the College of Eclectic Medicine and Surgery in Cincinnati, and again the next year, after which time he re- mained in Cincinnati, In 1859 ^e became profes- sor of anatomy in the Eclectic Medical Institute, with which the College of Eclectic Medicine and Surgery had merged, and two years later was given the chair of surgery, which he held until his death. As a surgeon he attained distinction and was called to all parts of the United States to per- form operations. Though operating in the days prior to surgical asepsis, his success was remark- able, owing to his skill in diagnosis, accurate knowledge of anatomy, fearlessness, steady hand, and remarkable surgical judgment For many years he wrote voluminously, not only concern- ing surgery, but on a wide range of subjects. Natural history still claimed a share of his in- terest He was a member of the American Asso- ciation for the Advancement of Science, and the Cincinnati Society of Natural History, before Howe which bodies he presented many papers. His editorials and leading articles were a feature of the Eclectic Medical Journal for more than thirty years. A work in manuscript by him, designed for children, was published by his wife after his death, Conversations on Animal Life (1897). Among the textbooks prepared by him are A Practical and Systematic Treatise on Fractures and Dislocations (1870), Manual of Eye Surgery (1874), Art and Science of Surgery (1876), Operative Gynaecology (1890). Oi his Art and Science of Surgery, Dr. Harvey W. Felter wrote: "While science moves on and new discoveries re- place old theories and methods—and some of Dr. Howe's will go with them—yet will this book re- main a delightful and valued repository of sur- gical lore stored in choice and chaste language" (post, p. 120). Though extremely conservative in the use of medicines Howe developed many substances of permanent value. He died Jan. 16, 1892, of carbuncle upon the neck, having delayed calling surgical aid until it was too late to save his life, and was buried at Paxton, Mass. He was married, Feb. 2, 1858, to Georgiana Lakin of Paxton. [D. W. Howe, Howe Geneals. . . . John Howe of i my luyq.} J.J.. w. jt'citci, uwi/t. uj~ tns Lloyd Library of Botany, Pharmacy and Materia Medica, No. 19f 1912; Cincinnati Commercial Gazette. Jan. 17. 1802.] J.U.L. HOWE, ELIAS (July 9, iSip-Oct. 3, 1867), inventor, was born in Spencer, Worcester Coun- ty, Mass., the son of Elias and Polly (Bemis) Howe, and a descendant of John Howe, of Sud- bury, who became a freeman of Massachusetts Bay Colony in May 1640 and died at Marlboro in 1680. Elias Howe, Sr., was a farmer and the owner of a small grist-mill and a sawmill. Howe went to school occasionally in the winter time and worked on the farm and in the mills. The machinery of the latter interested him particu- larly, and he liked nothing better than to tinker with it and make repairs. When he was twelve years old his father could not afford to keep him in clothes any longer and hired him out to a neighboring farmer. Poor health and lameness prevented him from doing heavy farm work, and a year later he returned home to help in the saw- and grist-mills. Ambitious to learn more about machinery, he went to Lowell, Mass., in 1835 and became an apprentice in an establishment that manufactured cotton machinery. The panic of 1837 severed this connection and Howe went to Cambridge, Mass. Here he found work in a machine-shop where he operated a newly invent- ed hemp-carding machine. After a few months he went to Boston and became an apprentice of 284