Howe Four of her six children survived her—Florence Marion Howe Hall [g.t/.], Henry Marion Howe [q.v.], Maud, the wife of John Elliott [q.v.~], and Laura Elizabeth, the wife of Henry Richards. The youngest, Samuel, born in 1859, had died in early childhood; the eldest, Julia, wife of Michael Anagnos [g.v.], in 1886. [L. E. Richards and M. H. Elliott, Julia Ward Howe (2 vols., 1015) ; L. E. Richards, Two Noble Lives (copr. 1911) ; M. H. Elliott, The Eleventh Hour in the Life of Julia Ward Howe (1911) ; Heroines of Modern Progress (1913); Women Who Have Ennobled Life (1915); Memorial Exercises in Honor of Julia Ward Howe, Held in Symphony Hall, Boston, on Sunday Evening, fan. 8t 1911 (1911) ; Bliss Perry, commemora- tive tribute in Proc. Am. Acad. of Arts and Letters, and of the Nat. Inst. of Arts and Letters, vol. I (1913).] M.S.G. HOWE, LUCIEN (Sept. 18, i848-Dec. 27, 1928), ophthalmologist, founder of the Buffalo Eye and Ear Infirmary, author of the Howe Law in the state of New York, and donor-in-chief of the Howe laboratory for ophthalmic research at Harvard University, was born at Standish, Me., the second son of Col. Marshall Spring Howe, U. S. A., and of Anne (Cleland) Howe. He sprang from a stalwart ancestry. His mother was descended from Dr. Andrew Turnbull, one of the first English settlers in Florida following the termination of Spanish rule and the builder of the town of New Smyrna on the east coast of Florida. Through his father he was descended from John Howe who was an early settler at Sudbury, Mass. Albion Parris Howe [q.v.~\ was his uncle. Lucien spent his boyhood on the fron- tier in New Mexico, where his father was gar- risoned. Later he was placed under the tutelage of a Unitarian minister at Topsham, Me. After graduating from Bowdoin College in 1870, and after studying medicine at Harvard and at the Bellevue Hospital in New York, he went to the medical centers of Europe for further study. His first contact was at Edinburgh with Lister, who was then establishing the antiseptic era in surg- ery. Completing his studies with Helmholtz and other masters in the clinics at Heidelberg, Ber- lin, and Vienna, he decided to specialize in the practice of ophthalmology, and in 1876 he found- ed the Buffalo Eye and Ear Infirmary, an insti- tution in which he was the dominant personality for fifty years. In 1879, at the age of thirty-one, he was made professor of ophthalmology at the University of Buffalo, and in 1885 he was ap- pointed ophthalmic surgeon at the Buffalo Gen- eral Hospital. In 1893 he married Elizabeth M. Howe of Cambridge, Mass. In 1890, after working for ten years toward the reduction of widespread blindness in babies, Howe was instrumental in securing the enact- ment pf the Howe bill by the legislature of New Howe York state. Under this law, for the first time in America, every attendant at childbirth was re- quired under heavy penalty to apply prophylactic drops to the eyes of newborn children. Other states followed this example, and the blindness from ophthalmia neonatorum in the United States dwindled to a fraction of its former magnitude. In 1896, by invitation, Howe delivered a resume of this work to the Societe Franchise d'Ophthal- mologie at Paris. Although the organization be- stowed upon Howe an honorary presidency, a courtesy never before extended to an American, it nevertheless objected to legalizing such meas- ures in France on the ground that they were an invasion of personal liberty. Howe's final medi- cal achievement was the foundation in 1926 of a research laboratory at Harvard University for investigation of diseases of the eyes. He con- tributed $250,000 toward its endowment, while the General Education Board and the Harvard Corporation added sufficient money to make the total fund $500,000. In recognition of his interest in hereditary blindness, which was the subject of the first publication from the laboratory, Howe was made president of the Eugenics Research Association in 1928, His published studies in- clude a two-volume work, The Muscles of the Eye (1907-08), Universal Military Education and Service (1916), and more than one hundred and thirty scientific papers. [Trans. Am. Ophthalmol. Soc.t vol. XXVII (1929); Archives of OphthalmoL, n.s. I, no. 2 (1929); Klinische Monatsblatter fur Augenheilkunde, LXXXII (1929) ; Elizabeth M. H. Howe, Frontiersmen (1931); D, W. Howe, Howe Geneals. . .. John Howe of Sudbury and Marlborough, Mass. (1929); the Bowdoin AtumnHs, Jan. 1929; Boston Transcript, Dec. 28, 1928, N. Y+ Times, Dec. 29, 1928.] J,H.W. HOWE, MARK ANTHONY DeWOLFE (Apr. 5, i8o8-July 31,1895), bishop of the Prot- estant Episcopal Church, was born in Bristol, R. L, the only child of John and Louisa (Smith) Howe, the latter a sister of Bishop Benjamin Bosworth Smith [q&."\ of Kentucky. He was a descendant of James Howe who emigrated from England and was admitted freeman of Roxbury, Mass., in 1637, later moving to Ipswich. John Howe's father, Capt Perley Howe, had mar- ried Abigail DeWolf, a sister of James DeWolf [q.v.l, whose father, Mark Anthony D'Wolf, had come to Bristol from Guadeloupe, whither his father, Charles, born in Lytne, Conn., had emigrated. The D'Wolfs were descendants of Balthasar, who settled in Connecticut rery early. Mark Howe studied at the local academy, at Phillips Academy, Andover, Mass., and at pri- vate schools. At the age of sixteen he entered Middlebury College, VenpQBt After two years 293