James equal to the demands of laboratory research in physiology. Unable to engage continuously in systematic instruction or research, he read wide- ly both in science and in German literature, and was at the same time profoundly stirred by his visits to the Dresden and Berlin galleries. He was, as always, fascinated by the manifesta- tions of human nature and of national character- istics in the life about him. The effect of this scattering of interests, together with the brood- ing induced by his unstable health, deepened the philosophical interests which he had caught from his father and to which he was predisposed by temperament. James returned to Cambridge in November 1868, and obtained his medical degree in the fol- lowing June. There followed a prolonged period of ill-health and nervous depression, which, like most such intervals in James's career, bore abundant fruit. It was clear that his interest was in the biological sciences rather than in medical practice, yet the weakness of his eyes and back forbade the use of the microscope or long hours of standing in a laboratory. But the amount and the quality of the reading on science, literature, and philosophy which James accomplished dur- ing these years of supposed incapacity exceeded the aspirations of most able-bodied men. In the midst of this period (probably in 1870) there occurred a crisis which was in part neurasthenic and in part intellectual. He was delivered from melancholia, and also from philosophic doubt. The latter effect he attributed to the reading of Charles Renouvier's Traite de Psychologic Ra- tionelle (1859), which converted him to a belief in moral freedom as an hypothesis to be actively adopted. In the fall of 1872 James was appointed in- structor in physiology in Harvard College and for the next ten years he taught comparative anatomy, comparative physiology, and hygiene. Lest the discontinuity of his development be ex- aggerated it must be remembered that biological science was at this time closely connected with both philosophy and psychology, as was indi- cated by the vogue of Herbert Spencer. The theory of evolution which w'as the central topic in general biology raised the issue of philosophi- cal materialism, and James's attention to biology thus prepared him for the course on the "Phi- losophy of Evolution," which he inaugurated in 1879. Psychology, on the other hand, was get- ting a fresh impulse from the physiology of the senses and the nervous system, topics on which James placed special emphasis both in his study and in his teaching, and to which his attention bad already been drawn, while in Germany in James 1868, by the work of Helmholtz and Wundt. In 1875 ne announced in the department of natural history a course for graduates on the "Rela- tions between Physiology and Psychology," and in the following year he added an undergraduate course on the same subject. These courses were transferred to the department of philosophy in 1877, and in 1880 James himself was similarly transferred and became assistant professor of philosophy. This instruction in physiological or biological psychology was recognized as a new departure and was viewed with some suspicion by philosophers of the older schools. In connec- tion with these courses, perhaps as early as the autumn of 1876, James created what best de- serves to be called the first American laboratory of psychology, and one of the first in the world. It was during this and the following year that G. Stanley Hall [g.z/.] carried on his studies at Harvard, under Bowditch and James. Hall's in- terests were more consistently experimental than James's, and the former founded a better equipped and more active laboratory at the Johns Hopkins University in 1882. Through the in- fluence of James and Hall, and that of the con- temporary German movement upon visiting American students, psychological laboratories began to multiply rapidly in the United States towards 1890. James married Alice Howe Gibbens on July 10, 1878. She was distinguished by the serenity of her disposition, as well as by her wit and beauty; and the companionship and protection which his family life provided were in no small measure responsible for the fruitfulness of James's subsequent career. Of his five children, one died in childhood, three sons and a daughter survived him. In June of the year of his mar- riage he had contracted with Henry Holt & Company to prepare a book on psychology. This finally appeared in 1890, as The Principles of Psychology, and during the twelve years' inter- val it was the author's major task. James's trips to Europe were too frequent to enumerate, but that taken during the summer of 1880 and his longer residence abroad during the year 1882- 83 were of peculiar importance in his develop- ment He was already known in Europe, in France through his articles in the Critique Phi- losophique, in England through his articles in Mind. He had entered into correspondence with many of his European colleagues. The visits of 1880 and 1882 brought him for the first time, however, into personal contact with them; and, as was characteristic of James's social relations, acquaintance quickly ripened into affectionate and enduring friendship. In August 1880 he